The PROG port (right side) is for Zen Studio only. If it's connected during gameplay, the Zen enters programming mode and drops your controller connection. Always unplug PROG before playing.
Many USB cables only charge and don't transfer data. If the Zen won't connect or show up in Zen Studio, try a different cable. The cable that came with your controller always works.
Setting everything to 5 causes mods to fight each other. AI Insta-Stop on Auto mode can cancel fades. AI Auto Tempo interferes with button shooting. Start with balanced settings, adjust one at a time.
Increase deadzone to 8–10% in 2K settings. If it persists, the controller itself has stick drift.